Charcot-Leyden crystals are associated with which type of airway inflammation?

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Charcot-Leyden crystals signal eosinophil-dominated airway inflammation. They form from eosinophil proteins released when these cells degranulate during allergic responses, such as asthma. Seeing these crystals in sputum or bronchial secretions reflects an eosinophilic inflammatory environment, which is not typical of neutrophil-rich bacterial infections, lymphocyte-dominated chronic processes, or fibrotic scar tissue.