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Multiple Choice

In adults with cystic fibrosis, which bacterium is commonly isolated?

In adults with cystic fibrosis, the airways’ thick, dehydrated mucus and impaired clearance create a niche where certain bacteria can persist. The organism that most commonly becomes a chronic colonizer in the CF adult lung is Pseudomonas aeruginosa. It frequently establishes long-term, biofilm-forming infections, often in mucoid strains that resist treatment and drive ongoing lung deterioration. While other bacteria such as Staphylococcus aureus and Haemophilus influenzae are seen earlier in life, and Klebsiella can occur, Pseudomonas aeruginosa is the predominant and most consistently isolated pathogen in adults with CF.

In adults with cystic fibrosis, the airways’ thick, dehydrated mucus and impaired clearance create a niche where certain bacteria can persist. The organism that most commonly becomes a chronic colonizer in the CF adult lung is Pseudomonas aeruginosa. It frequently establishes long-term, biofilm-forming infections, often in mucoid strains that resist treatment and drive ongoing lung deterioration. While other bacteria such as Staphylococcus aureus and Haemophilus influenzae are seen earlier in life, and Klebsiella can occur, Pseudomonas aeruginosa is the predominant and most consistently isolated pathogen in adults with CF.