The Ghon focus is a primary TB lesion located in which organ?

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Multiple Choice

The Ghon focus is a primary TB lesion located in which organ?

The main idea is that the Ghon focus is the initial lesion of primary tuberculosis that forms in the lung parenchyma. When TB bacilli are inhaled, they settle in the lung, typically in the subpleural area of the lower lobes, where they provoke a small caseating granulomatous lesion—the Ghon focus. This pulmonary focus is usually accompanied by regional lymph node involvement, forming the Ghon complex. Over time, calcification can occur in both the lung lesion and the involved nodes, yielding a Ranke complex on imaging. It is not located in the liver or brain; those sites represent extrapulmonary TB, whereas the Ghon focus specifically denotes a lesion in the lung.

The main idea is that the Ghon focus is the initial lesion of primary tuberculosis that forms in the lung parenchyma. When TB bacilli are inhaled, they settle in the lung, typically in the subpleural area of the lower lobes, where they provoke a small caseating granulomatous lesion—the Ghon focus. This pulmonary focus is usually accompanied by regional lymph node involvement, forming the Ghon complex. Over time, calcification can occur in both the lung lesion and the involved nodes, yielding a Ranke complex on imaging. It is not located in the liver or brain; those sites represent extrapulmonary TB, whereas the Ghon focus specifically denotes a lesion in the lung.

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