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Multiple Choice

Which cytokine drives eosinophil recruitment?

Eosinophil recruitment is driven by a cytokine that specifically promotes the development, maturation, and survival of eosinophils, and directs their movement to inflamed tissues. IL-5 fits this role precisely: it is produced by Th2 cells and other sources during allergic and parasitic responses, acts on the eosinophil lineage via the IL-5 receptor, and stimulates bone marrow production, prolongs eosinophil survival, and enhances their recruitment to sites of inflammation. The other cytokines listed have broader inflammatory roles or support T cell growth but do not specifically drive eosinophil recruitment.

Eosinophil recruitment is driven by a cytokine that specifically promotes the development, maturation, and survival of eosinophils, and directs their movement to inflamed tissues. IL-5 fits this role precisely: it is produced by Th2 cells and other sources during allergic and parasitic responses, acts on the eosinophil lineage via the IL-5 receptor, and stimulates bone marrow production, prolongs eosinophil survival, and enhances their recruitment to sites of inflammation. The other cytokines listed have broader inflammatory roles or support T cell growth but do not specifically drive eosinophil recruitment.